This funding supports SenNet Discovery and Validation Centers to define, refine, and validate cellular senescence signatures and biomarkers relevant to tissues and diseases. Centers will generate molecular, cellular, and spatial datasets, validate senotypes using experimental systems, and characterize responses to senescence-related perturbations and therapies. The program also includes consortium-wide organizational and outreach activities.
Eligible applicants include a wide range of U.S. government entities, educational institutions, nonprofits, for-profit organizations, tribal governments, and certain non-U.S. entities. Specific eligibility details are provided in the announcement.