This funding supports centers to systematically perturb genomic variants and assess their impact on genome function and phenotype using high-throughput methods. Funded centers will develop robust data processing pipelines and collaborate within the IGVF Consortium to coordinate assays, variants, and cell types, advancing understanding of variant effects from molecular to organismal levels.
Eligible applicants include a wide range of U.S. government entities, educational institutions, nonprofits, for-profit organizations, small businesses, and foreign organizations or components of U.S. organizations. Foreign subawards/subcontracts are not allowed unless part of designated internationa