This initiative funds research to develop and optimize targeted drug delivery systems such as engineered nanoparticles and extracellular vesicles to deliver therapeutics precisely to hard-to-reach locations like the blood-brain barrier, CNS, placenta, retina, or tumors. Projects should assess biodistribution, off-target effects, functional cargo activity, and optimal administration routes using multi-organ microphysiological systems.
Eligible applicants include state and county governments, independent school districts, public and private higher education institutions, Native American tribal governments and organizations, public housing authorities, nonprofits with 501(c)(3) status, for-profit organizations excluding small busin