This funding supports investigator-initiated Phase I clinical trials for diagnostic and therapeutic interventions addressing heart, lung, blood, and sleep disorders in adults and children. It covers clinical trial start-up, implementation, and final preclinical activities needed for trial readiness. The award uses a bi-phasic, milestone-driven mechanism where the initial phase focuses on pre-trial activities such as stability and shipping studies and site training. Trials can be single or multisite.
Eligible applicants include a wide range of organizations such as public housing authorities, institutions of higher education, small businesses, government entities, nonprofits, tribal organizations, and certain federal and regional organizations. Both domestic and some non-domestic entities may ap
