This funding opportunity supports research investigating the etiology, biological mechanisms, and early detection strategies of sporadic non-hereditary early-onset cancers in adults aged 18 to 49. Projects should focus on environmental and lifestyle factors driving incidence increases, underlying biological responses, and improved risk identification methods. Both exploratory and standard research projects are supported to advance understanding and prevention.
Eligible applicants include U.S. state, county, city, and special district governments; educational institutions; Native American tribal governments and organizations; nonprofits; for-profit organizations including small businesses; and foreign organizations without foreign subawards/subcontracts.