This funding opportunity supports ambitious projects aimed at comprehensive functional validation of newly identified therapeutic targets for Alzheimer's Disease-Related Dementias. It funds development of customized technologies, models, and protocols to modulate candidate targets and assess their physiological effects in relevant disease models. The initiative uses a phased award mechanism to de-risk translational research and accelerate novel therapeutic strategies, emphasizing rigor, reproducibility, and cross-validation across labs.
Eligible applicants include state, county, city, and special district governments; public and private higher education institutions; Native American tribal governments and organizations; nonprofits; for-profit organizations including small businesses; and certain other specified entities. Foreign in
