Supports research projects investigating how neural exposome factors such as environmental toxins, sleep, circadian rhythms, stress, and real-world conditions contribute mechanistically to Alzheimer’s disease-related dementias pathology and resilience. Encourages studies on synergistic actions of multiple exposome factors, mechanistic pathways linking exposures to ADRD risk and resilience, lifespan exposure, and neurological health disparities. Supports mechanistic, translational, and human subjects research but excludes NIH-defined clinical trials.
Eligible applicants include a wide range of U.S. government entities, educational institutions, nonprofits, for-profit organizations, tribal governments, and non-domestic entities. Specific eligibility includes state, county, city governments, tribal organizations, nonprofits, small businesses, and
