This initiative funds research to develop, optimize, validate, and apply germline and somatic gene-editing approaches in experimental models that replicate key aspects of human brain anatomy, circuitry, cognition, behavior, and lifespan. It emphasizes advancing human-derived New Approach Methodologies and cross-species comparisons to better understand brain function and diseases such as autism and schizophrenia.
Eligible applicants include a wide range of government entities, educational institutions, nonprofits, for-profit organizations, tribal governments, and other specified organizations including foreign institutions. Specific eligibility details are extensive and diverse.
