This grant funds clinical trials to evaluate safety and efficacy of tolerogenic strategies in transplantation, allergic diseases, asthma, and autoimmune diseases. It also supports mechanistic studies of immune tolerance and development of immune assays to monitor tolerance induction and loss. The program aims to improve prevention and treatment of immune system mediated diseases through collaborative clinical research.
Eligible applicants include a wide range of U.S. government entities, educational institutions, tribal governments and organizations, nonprofits, for-profit organizations including small businesses, faith-based and community organizations, regional organizations, federal agencies, U.S. territories,